HEMODIALYSIS

This study is testing a new device called the InnAVasc graft, which helps connect kidney failure patients to dialysis machines. About 133 adults with end-stage kidney disease will receive the graft and be followed for 2 years. The main goal is to see if the graft stays open and w…

This study tests whether a new medication called AV-001 can protect the brain in people who undergo regular hemodialysis. Dialysis can sometimes cause brain injury, leading to memory problems or slower thinking. The drug works by strengthening blood vessels in the brain and reduc…

This study tests whether special filters (sorption technologies) can lower inflammation in people on long-term hemodialysis for kidney failure. About 60 adults with high inflammation levels will receive the filter during their regular dialysis sessions. The main goal is to see if…

This study tests whether giving thyroid hormone (levothyroxine) to dialysis patients with slightly high TSH levels can improve their quality of life, physical strength, and heart health. About 336 adults on hemodialysis will receive either the hormone or a placebo for up to 24 mo…

This study tests whether a 12-week course of a multi-strain synbiotic (a mix of probiotics and prebiotics) can improve gut health in 30 adults on hemodialysis. The goal is to see if it can reduce harmful gut toxins and strengthen the gut barrier, which may lower inflammation and …

This study tests whether a manuka honey mouthwash can improve gum disease in people with kidney failure who are on dialysis. Gum disease is very common in these patients and can lead to tooth loss and inflammation. Researchers will measure gum attachment, bleeding, and a marker o…

This study tests whether royal jelly, a substance made by bees, can lower inflammation and slow cell aging in people with chronic kidney disease who are on hemodialysis. Researchers will measure changes in blood markers related to inflammation and aging. The study involves 30 adu…

This study looks at whether a special breathing exercise program can make respiratory muscles stronger and improve quality of life for people on hemodialysis. Fifty patients aged 50 to 60 who have been on dialysis for 1 to 3 years will take part. The goal is to see if these simpl…

This study tests whether progressive muscle relaxation exercises can reduce depression and fatigue in people receiving hemodialysis. About 60 patients will learn these simple, drug-free techniques and report their mood and energy levels. The goal is to see if this easy-to-do prac…

This study tests whether a 4-week mindfulness meditation program can improve sleep quality, reduce stress, and lessen symptoms in people receiving hemodialysis. About 50 adults on dialysis will either get meditation plus usual care or usual care alone. The goal is to see if this …

This study compares two types of dialysis—standard high-flux hemodialysis and hemodiafiltration—to see which one causes less tiredness and helps people aged 85 and older recover faster after treatment. Each participant will try both methods for three months, acting as their own c…

This study tests a 13-week program teaching dialectical behavioural therapy (DBT) skills to help adults on hemodialysis manage anxiety and improve mental well-being. About 35 participants who recently started dialysis or plan to start soon will join. The program will be offered i…

This study tests whether personalized support from an exercise teacher and a nurse can help people on hemodialysis become more physically active at home. The study will include 70 adults who have been on dialysis for less than a year. The goal is to see if this support leads to l…

This study looks at whether a 6-week aerobic exercise program can lower uric acid levels and improve daily function and quality of life in 32 adults aged 40-60 who are on hemodialysis. Participants will either do structured exercise or receive standard care. The goal is to find a…

This study is testing a new device called PatenSee that can check the health of dialysis access points without touching the patient. About 90 adults with kidney failure who need regular dialysis will take part. The device uses light and sound to see and hear the access point, and…

This study looks at whether changing the amount of magnesium in the dialysis fluid can reduce inflammation and blood cell activation during treatment. About 15 adults on hemodialysis will have their blood and the used dialysis circuit tested after sessions with different fluid co…